Cancer, with almost 10 million global deaths in 2020, is a major health concern. The Robert Bosch Center for Tumor Diseases (RBCT) focuses on lung, colorectal, pancreatic cancers and leukemia, considering their prevalence. Our collaboration ties with the Robert-Bosch-Hospital (RBK) and partners of the National Center for Tumor Diseases Southwest (NCT-SüdWest).
Molecularly, these cancers share similar traits like high KRAS and TP53 genetic mutations, and each responds differently to advanced treatments. Pancreatic cancer, particularly lethal, highlights the pressing need for targeted therapies and improved patient stratification. Conversely, colorectal cancer survival has surged, primarily due to early detection, but challenges persist in treatment responses.